10 Best glucosamine of 2020

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Glucosamine counselor

Properties and benefits of glucosamine

Glucosamine is an amino acid sugar that is a derivative or derivative of glucose. The backbone of D-glucose is replaced by an -NH2 amino group on the -OH group on the C2 carbon atom. This amino sugar is produced in the body and occurs in larger quantities in the menschlicken body, where it is mainly found in the joints. Here it can be found in the cartilage, in the synovial fluid and also in the connective tissue. In the body it gets out of the amino acid glutamineand synthesized from fructose-6-phosphate. There glucosamine is made mainly of everyday food ingredients in the body, it is about the products offered to Dietary supplements, The substance is said to have a soothing effect on joint pain and osteoarthritis. Since the actual cure for most claims is not proven, the substance should not be labeled as a drug in these cases. Nevertheless, forms glucosamine a peculiarity and is both: dietary supplement and drug.

Claims to effectiveness

There glucosamine Despite its synthetic route, it can be absorbed by the body via a fructose compound, where it also enters the metabolism. In contrast to many other nutritional supplements, it is actually a physiologically active substance. When marketed as dietary supplements, it is often suggested that glucosamine would be stored in the cartilage and in the cartilage fluid and thereby helps protect the cartilage, possibly even rebuild and thus improve the health of the joints. There is generally insufficient evidence for these allegations. For these reasons, glucosamine is considered as a dietary supplement in almost all products. For the marketing of food supplements in Germany very strict rules apply, making it inadmissible to make statements about a possible healing effect. Such statements can always recognize the seriousness of a provider. Only a few preparations under different brand names are actually approved as a drug and may then be advertised with a medically proven healing effect.

Evidence of effectiveness

In the past, a number of studies have been carried out to verify the efficacy of glucosamine using scientifically sound methods. Such blind and double-blind studies, which additionally randomly provide patients with glucosamine or a placebo, are the best way to study the efficacy of a substance and to identify potential side effects at an early stage. In several studies, the scientists came to different conclusions. This fact should be considered when taking it, especially if it is carried out in the form of a dietary supplement on own responsibility. Most studies have failed to confirm the claim that glucosamine reduces joint pain. Only one out of four larger studies resulted in a pain-relieving effect, but this is somewhat doubtful, as different concentrations were used, but all groups showed similar good improvements. Therefore, one should not be hoped for a pain-relieving effect on the joints! The results on arthrosis-related complaints showed somewhat clearer evidence of medical efficacy. In all studies it could be shown that an improvement occurs. Nevertheless, there are also different meaningful test results here. On average, the more pronounced the effects of glucosamine, the more severe the arthrosis-related symptoms are. On the one hand, these results are sufficient for approval as a drug, but on the other hand, they also show that malnutrition was likely to be present, as glucosamine can be produced in sufficient quantities in the body under normal circumstances.

side effects

Since glucosamine can be produced from food in the body itself, the Redel has a sufficiently effective mechanism to regulate the concentration. This makes an overdose difficult. It is recommended a daily maximum amount of 1250 mg or 1.25 grams and then shows no known side effects. It should be noted that there is no experience as to whether side effects can occur in children. This applies equally to the unborn, babies and adolescents. Also, about the transmission of glucosamine via breast milk is not known. For these reasons, self-medication with glucosamine as a dietary supplement should be avoided. An additional problem concerns the amounts in the preparations. These are regulated for medications, sometimes exceed the recommended daily allowance in products that are approved as dietary supplements. Since glucosamine is mostly obtained from crustaceans in industry, allergic reactions can occur.

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*Last update on 2020-11-04 / Affiliate links(we get a commission when you buy on amazon) / Images from Amazon Product Advertising API